What medication class is commonly used to treat uterine fibroids?

GnRH (gonadotropin-releasing hormone) agonists are commonly used to treat uterine fibroids due to their mechanism of action, which effectively reduces estrogen and progesterone production. This reduction results in a decrease in the size of the fibroids and helps alleviate symptoms associated with them, such as heavy menstrual bleeding and pelvic pain.

These medications work by binding to GnRH receptors in the pituitary gland, leading to an initial increase in gonadotropins, followed by a downregulation of these receptors and a subsequent decrease in hormone production. This hormonal manipulation can lead to a temporary state similar to menopause, reducing the size and symptoms of fibroids.

In contrast, the other options provided do not have a primary role in the treatment of uterine fibroids. Beta-blockers are typically used for cardiovascular conditions or certain anxiety disorders, ACE inhibitors primarily manage hypertension and heart failure, and antibiotics are prescribed for bacterial infections rather than for the treatment of fibroids. Thus, GnRH agonists are the most pertinent and effective class of medications for managing this specific condition.