Which of the following lab studies is commonly seen in menopause?

In menopause, it is common to observe low levels of estradiol coupled with elevated levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). This hormonal profile reflects the loss of ovarian function and its impact on the body's endocrine system.

As women approach menopause, the ovaries gradually decrease their production of estradiol, which is a key estrogen hormone. The decrease in estradiol levels is a direct result of the diminished ovarian reserve and hormone production. In turn, when estradiol levels drop, the feedback mechanism to the pituitary gland is disrupted, leading to a rise in FSH and LH as the body attempts to stimulate the ovaries to produce more estrogen. This increase in FSH and LH is a hallmark of menopause and indicates that the body is experiencing a shift in its hormonal balance due to the cessation of ovarian function.

The hormonal changes during menopause are important, as they not only underscore the transition into this phase of life but also help in diagnosing menopause through lab studies. Therefore, the profile of low estradiol with high FSH and LH is a classic finding in menopausal women.